摘要:<正> In this report, we mainly covered the following aspects of "Tissue organ regeneration and replication in situ": 1) Procedures of tissue organ regeneration and replication and replication in clinical practice; 2) The discover and existence of Potential Regenerative Cell (PRC); 3) The proliferation, differentiation and regeneration law of Potential Regenerative Cells; 4) Study procedure on tissue organ regeneration and replication from PRCs in vitro based on the model of full skin organ regeneration in situ after extensive deep burns; 5) With the well-established model of tissue organ regeneration and replication and replication in vitro, set up the method and technology of searching life regenerative substances required in tissue organ regeneration and replication in situ.In this study, first, the whole human body is divided into 206 function units, which are the "Tissue Organ" in regeneration study. Then the histology foundation of tissue organ regeneration and replication in situ is set up. In order to
摘要:目的观察Spectra双脉冲祛斑后使用美宝湿润烧伤膏(moist exposed burn ointment,MEBO)的临床效果。方法将200例使用Spectra祛斑的患者,随机分为治疗组和对照组,各100例。治疗组治疗后创面外用MEBO,每6h一次,共使用3d,3d后每日以冷水洁面;对照组治疗后冰敷0.5h~1h,其后每日以冷水洁面。观察两组在治疗后止痛效果、创面愈合时间的差别。结果治疗组100例中19例出现疼痛,81例无痛。对照组100例中75例出现疼痛,25例无痛。治疗组平均创面愈合时间为9.53天,对照组平均创面愈合时间为10.65天。治疗组止痛效果、创面愈合时间与对照组比较有显著统计学差异(P<0.01)。结论美宝湿润烧伤膏(MEBO)应用于Spectra双脉冲祛斑后创面,有止痛、促进创面愈合的作用,临床效果好。
摘要:BACKGROUND? There is growing evidence of improved healing of full- and partial-thickness cutaneous wounds in wet and moist environments. Retention of biologic fluids over the wound prevents desiccation of denuded dermis or deeper tissues and allows faster and unimpeded migration of keratinocytes over the wound surface. It allows also the naturally occurring cytokines and growth factors to exert their beneficial effect on wound contracture and re-epithelialization. Despite all of these documented benefits, applying the moist healing principles to large surface areas, in particular to large burns, is hindered by the major technical handicap of creating and maintaining a sealed moist environment over these areas. METHODS? From January to September 2001, healing of partial-thickness skin graft donor sites was studied in a prospective comparative study of two types of moist dressings, Tegaderm (3M Health Care, St. Paul, MN), a semipermeable membrane occlusive dressing, and moist exposed burn ointment (MEBO) (Julphar; Gulf Pharmaceutical Industries, United Arab of Emirates), an ointment that can provide a moist environment without the need of an overlying occlusive dressing. Healing was assessed both clinically and with serial measurements of transepidermal water loss (TEWL) and moisture. Following healing, scar quality was evaluated by two members of the team separately using a visual analog scale. Results were statistically analyzed. RESULTS? Faster healing was observed clinically with MEBO application. Physiologic healing as determined by TEWL measurements occurred at an extremely significant earlier stage for MEBO, and this was associated with better scar quality, demonstrating a positive relationship between function and cosmetic appearance. Moreover, the ointment is definitely easier to apply than the occlusive self-adhesive membrane, which requires some degree of dexterity and expertise. CONCLUSION? MEBO application is an effective and valid alternative to conventional occlusive dressings. Moreover, the observed improved anatomic and physiologic healing indicates that MEBO may have a positive effect on healing more that the mere fact of passive moisture retention.
摘要:Burn rehabilitation; Hand function; Scar evaluation; MEBO