摘要：OBJECTIVE: Wound healing in burn wounds presents a challenge in healthcare, and there is still a lack of alternatives in topical burn wound treatments. - The purpose of this study was to evaluate the efficacy of a new therapeutic ointment (MEBO) in the treatment of partial thickness burns. METHODS: 40 patients received either topical treatment with Moist Exposed Burn Ointment (MEBO) or standard Flammazine treatment. All patients suffered from partial-thickness burn injuries (< 20% TBSA). Wounds were evaluated for 60 up to days regarding wound healing, water loss, inflammation, and pain alleviation. RESULTS: For transepidermal water loss, there was a difference of 2.3 gr/m2/h between MEBO, and Flammazine, favoring MEBO. However, this difference was not statistically significant (p=0.78). For all secondary efficacy parameter results were similar. - CONCLUSIONS: This study showed that MEBO ointment for topical treatment of burn injuries presents an attractive alternative for the topical treatment of limited partial thickness thermal burns.
摘要：Burn injuries are associated with anatomically within physiologically infections and biochemically within immunologically defect in hepatic functions during direct action on locally and systematic role of blood elements and liver enzymes. These defects represented the cellular response due to burn injuries. Aim of study: to assess the treatment and antioxidant action of MEBO ointment in medical therapy ,such as burn therapy. Methods: The study was performed by 66 burn patents(male) received treatment with ointment MEBO(100g)twice daily for two weeks and all patients have thickness burn injury, age ranged(15-65years for all subjects) and 50 men healthy control subjects ,So one day post burn samples were collected for hematological &biochemical parameters in kirkuk city at Azaadi hospital ,and this study done from march to December 2019 . Results: Leukocytes count (WBC), Neutrophil, lymphocyte,) and erythrocyte sedimentation rate ( ESR) were increased, while red blood cells count (RBC), hemoglobin (HB) were decreased after burn injury. Creatinine and potassium element are increased significantly, while Sodium element was decreased and significantly increased in the liver enzyme and glutathione after treatment when MDA significantly decreased .Conclusion: This study concluded that blood parameters and liver functions were altered due to burn injuries and these modulations attributable to the lipid peroxidation(MDA), while the liver enzyme signaling of hepatic activity for glutathione synthesis for curbing the free radicals after treatment by MEBO ointment ,this productive mechanism may be new defect liver mechanism for burn injury.
摘要：Background: Burns are considered a serious health affection that leads to several consequences affecting a person both physically and emotionally. Herbal and traditional medicine have become popular remedies among patients worldwide. Aim: This study explores common practices followed in burns as first aid management. Methods: A cross-sectional study was conducted in the Eastern province of Saudi Arabia using a designed questionnaire distributed electronically through different social media. The questionnaire consisted of socio-demographic details, history of burns, causative material, and practices followed in response to burns. Results: 461 individuals have participated in this study. The commonest reason for burns was hot water or steam. The majority of the respondents (63%) had a satisfactory response to self-aid alone at home. The most common first aid options for managing burns at home were cold water alone 195 (42%), any sort of cream alone 177 (38%), or both 317 (69%). Overall, the result shows no statistically significant difference between the outcome of burn injury and the most commonly used burn aids. Conclusions: Most people use creams and water as the first-aid management of burns, while a good number of people use traditional medicine. Overall, people who receive hospital treatment after getting first aid at home give a better outcome.