摘要：Background:? Traditional Chinese herbal ointment has significant curative effect and few side effects in the treatment of perianal eczema (PE). Currently, there is no systematic evaluation on the treatment of PE with traditional Chinese medicine ointment. The current aim is to systematically evaluate the efficacy of traditional Chinese medicine ointment in the treatment of PE through meta-analysis. Methods:? Randomized controlled trials on the treatment of PE with Chinese herbal plaster were included in the meta-analysis, which was searched in Chinese and English databases up to March 1, 2023. The search will be conducted in accordance with the object of PICOS framework. Two research will independently use EndnoteX9 to extract the data and evaluate the quality assessment of included trails. Meta-analysis was performed using Revman5.4.1 provided by Cochrane Collaboration; when the outcome indicator is a dichotomous variable, relative risk (RR) was used as the effect size; when the outcome indicator is a continuous variable, weighted mean difference (MD) was used as the effect size, each effect size should be expressed as 95% confidence interval (CI). Results:? The results of meta-analysis showed that: The total effective rate of PE (RR: 1.22, 95% CI: 1.15, 1.30, P < .01; I2 = 32%, Q = 0.17). The cure rate of PE (RR: 3.37, 95% CI: 2.30, 4.94, P < .01; I2 = 21% Q = 0.26). The recurrence rate of PE (RR: 0.25, 95% CI: 0.13, 0.48, P < .01; I2 = 31%Q = 0.23). Itchy points (MD: 0.04, 95% CI: ?0.19, 0.27; I2 = 26%) Skin damage area (MD: ?0.37, 95% CI: ?0.56, ?0.19; I2 = 26%). Skin damage form (MD: ?0.59, 95% CI: ?0.81. ?0.36; I2 = 0%). Conclusion:? A total of 11 articles were included in this study for meta-analysis, and the results showed that Chinese medicine ointment is more helpful in improving the skin lesion area and skin damage form, significantly improve the response rate and cure rate, reduce the recurrence rate. Chinese herbal ointment has guiding significance for clinical practice which deserve to use ointments by further experimental and clinical investigation.

摘要：Aim This study aimed to investigate the clinical efficacy of externally applied Traditional Chinese Medicine (TCM) on diabetic foot. Methods We searched the China Knowledge Network (CNKI), Wanfang Database, PubMed and Web of Science from inception to July 31, 2022, to find all randomized control trials (RCTs) related to externally applied TCMs in diabetic foot treatment. Information about the total effective rate, healing rate, and healing time were extracted. In addition, the relative risk (RR)/odds ratio (OR) or standardized mean difference (SMD) and 95?% confidence interval (CI) were calculated. Results Finally, a total of 34 RCTs including 3758 patients were included in this meta-analysis. There were 5 articles that reported hydropathic compress with astrogalin, 14 articles that reported MEBO burn cream, 9 articles that reported compound cortex phellodendri liquid and 6 articles that reported Shengji Yuhong ointment. Compared with the basic treatment, the externally applied TCM (astrogalin, MEBO burn cream, compound cortex phellodendri liquid and Shengji Yuhong ointment) combined with basic treatment improved the total effective rate (RR?=?1.31 [1.20, 1.42], P?<?0.0001) and healing rate (RR?=?1.84 [1.56, 2.17], P?<?0.0001) and shortened the healing time (SMD?=???2.51 [??3.39, ??1.63], P?<?0.0001). Conclusion Our systematic review and meta-analysis revealed that common TCM applied externally could significantly improve the clinical efficacy comparing to the basic treatment.

摘要：Background: Burn healing is dependent on good wound care management. Infection is one of the cause of wound healing failure. Infectious wound should be treated immediately. Binahong’s leaves is trusted as traditional herbal medicine which is considered capable to help wound healing process. Patient and Method: A 35 years old women suffer from scald and got 3% surface partial thickness burn at her right hand. The patient was initialy treated by application of MEBO. After a week patient came and felt uncomforted with the gauze. So, binahong’s leaves was patched on her wound to help the wound healing process. Result: After a week with binahong’s leaves therapy, the epithelialization is good and there was no infection. The result is satisfactory. Conclusion: This study shows that binahong’s leaves can be used to help wound healing process.

摘要：This study investigated the types of phytosterols that exists in the aerial and root parts of Echinops heterophyllus and explored the antibacterial effect of these phytosterols against some pathogenic bacteria in comparison with Moist Exposed Wound Ointment (MEBO?) and gentamicin.Plant was extracted and phytosterols were isolated and purified from the crude extract of Echinops heterophyllus by using chemical method. Thin Layer Chromatography (TLC) detected the presence of steroids in the aerial and roots part and gas chromatographymass spectrophotometer GC/MS analysis was used to identify some of these compounds and among them were beta-sitosterol and stigmasterol. Standard dilutions of the phytosterols isolated from Echinops heterophyllus were made from 10-100%; its antibacterial effect had been examined by seeded agar method against Staphylococcus aureus and Pseudomonas aeruginosa.The effect of these phytosetrols against Staphylococcus aureus was more potent than against Pseudomonas aeruginosa.The minimum inhibitory concentration (MIC) was seventy mg/ml and the minimum bactericidal concentration (MBC) was eighty five mg/ml. This study illustrates that sitosterol isolated from Echinops heterophyllus has a greater inhibitory effect on the test bacteria than gentamicine and closer results to MEBO?. It can be concluded in this study is a good step to show the types of phytosterols isolated from Echinops heterophyllus and the antibacterial effectof these phytosterols in vitro against Staphylococcus aureus and Pseudomonas aeruginosa.