摘要:The time profile of total proteins and albumin in line with two amino acids, Phe and Glu, are of great importance due to their indicative value of the healing and/or deterioration of burn wounds. In this experiment, rats exposed to scalding that produced a second-degree burn were divided into four groups: control, placebo, MEBO ointment, and copper (I) nicotinate complex ointment (an antioxidant anti-inflammatory) for four weeks. The three treatments showed noticeable similarities in the Phe profiles, with a slight drop 24 hours post burn, a peak elevation by the second week, and a slight, insignificant decline by the third week, with the placebo group showing highest values over normal (P< 0.05). In the Glu profile, large differences were observed: two set profiles, one representing MEBO and copper (I) nicotinate showed one peak in the second week, and the other representing placebo showed two peaks in the first and third weeks. Albumin and total protein time profiles showed the same trend throughout the whole experiment, and are in line with a reformed metabolic state parallel to wound closure. These results reveal that MEBO and copper nicotinate have comparable effects on wound healing in scald burns, and that plasma Glu profile is a better systemic indicator reflecting the regularity and steadiness of the healing process in MEBO and copper complex treatment.
摘要:目的探讨CO2点阵激光联合湿润烧伤膏治疗面部色素沉着的临床效果及安全性。方法选取河南整形美容医院2021 年10 月至2023 年10 月收治65 例面部色素沉着患者,依据治疗方式不同分为对照组(n=33)、观察组(n=32)。对照组接受CO2点阵激光治疗,观察组接受CO2点阵激光联合湿润烧伤膏,两组均治疗至创面愈合。比较两组面部色素沉着评分、皮肤性质评分、生活质量评分、氧化应激指标、不良反应等。结果 治疗后两组面部色素沉着评分、皮肤性质评分均比治疗前高,且观察组比对照组更高;治疗后两组生活质量评分均比治疗前高,且观察组比对照组更高;治疗后两组血清丙二醛、过氧化脂质水平均比治疗前低,且观察组比对照组更低,血清超氧化物歧化酶均比治疗前高,且观察组比对照组高;观察组治疗期间不良反应总发生率比对照组更低,上述数据差异均有统计学意义(P<0.05)。结论 CO2点阵激光联合湿润烧伤膏可改善面部色素沉着患者皮肤性质,促进色素沉着恢复,调节氧化应激指标水平,提高患者生活质量,安全性较高。
摘要:目的:探讨CO2点阵激光联合湿润烧伤膏治疗创伤性瘢痕的临床疗效。方法:选取73例创伤性瘢痕患者,年龄21-35岁,对照组(35例)给予CO2点阵激光术治疗,术后涂抹莫匹罗星软膏护理,观察组(38例)采用CO2点阵激光术联合湿润烧伤膏治疗。通过对患者治疗后3个月的体征、疗效及3个月内不良反应的发生情况评价CO2点阵激光术联合湿润烧伤膏对创伤性瘢痕的疗效。结果:与治疗前相比,两组治疗后3个月的VSS评分均明显提高(P<0.05),但两组间VSS评分相比差异没有统计学意义(P>0.05)。治疗后3个月,观察组的治疗有效率明显高于对照组(P<0.05),治疗后3个月期间,观察组的不良反应发生率明显低于对照组(P<0.05),色素沉积和创面感染是主要的不良反应症状。结论:CO2点阵激光技术联合润湿烧伤膏对于创伤性瘢痕具有良好的治疗效果,且安全性高。
摘要:本文报道我院妇产科和烧伤科共同协作,在门诊于1992年2月初至1995年4月底,采用CO<sub>2</sub>激光离断子宫颈息肉根蒂配伍MEBO纱条上药的方法,共治疗子宫颈息肉门倒,获得了一次性治愈的满意效果,治愈率为100%。笔者认为:本法水中病人不感任何痛苦,无出血。未毕配伍MEBO纱来贴敷根蒂残端之灼焦创面,可保障灼伤创面无感染,使创面下残存的有生机上皮组织按生理性地进行修复,愈合无废痕。临床效果可靠,无副作用,经随访半年,无复发,颇值妇科临床进步推广使用。