摘要:目的探讨严重烧伤(重度和特重度)急性渗出期,采用烧伤湿性医疗技术(MEBT/MEBO)防治早期休克的临床效果。方法总结5年来,我院对56例严重烧伤急性渗出期,采用MEBT/MEBO治疗的病历资料,分析他们的休克发生率和液体实际输入量,推导出他们的补液计算参数。结果 56例患者均平稳度过休克期,未发现休克病例,心、肾功能正常;第1个24h每1%烧伤面积计算补液参数为0.9~1.25,第2个24h为0.5~0.65。结论严重烧伤急性渗出期采用MEBT/MEBO治疗,可有效防治早期休克,减少输液量。
摘要:目的:探讨三种治疗方法对大面积烧伤病人的治疗效果。方法:采用SD-Zn糊膏、0.5%碘伏、MEBO治疗大面积烧伤160例。结果:SD-Zn及碘伏组共80例创面全部愈合,其中23例遗留疤痕增生,MEBO组80例全部治愈,治疗时短,仅7例轻度疤痕增生。结论:三种疗法中,MEBO湿润烧伤膏治疗大面积烧伤,方法简单,疗效可靠,便于推广应用。
摘要:Objective: From molecular, cell and systemic clinical treatment three levels, this report revealed the mechanism of wound healing, the basic theory and the importance of clinical practice for the Burn Regenerative Therapy with MEBT/MEBO (BRT & MEBT/MEBO).Method: This report analyzed the importance and clinical curative effect for standardized appliance of BRT & MEBT/MEBO from two key points: 1) Liquefaction of necrotic tissue from burn wound; 2) Skin regenerationin situ. Result: There are three necessary conditions for skin physiologically repair and regeneration of burn wound: 1) The formation of moist physiological environment on burn wound; 2) The material foundation of life regenerative substances and histology for keratin-19 stem cells' regenerationin situ; 3) Standardized procedures and appliance of BRT & MEBT/MEBO, which is the guarantee of burn wound healing physiologically. Conclusion: The theory of “Potential Regenerative Cell" and the technique of “Stem cellin situregeneration" are ...
摘要:Objective: To investigate the mechanism of the effect of Moist Exposed Burn Therapy (MEBT) and Moist Exposed Burn Ointment (MEBO) on the spontaneous repair and healing of superficial third degree burn wound involving fatty layer. Method: A series of skin tissue samples were taken from deep burn wounds of 2 cases. Immunocytochemistry method, biotin-avidin DCS system, and indirect immunofluorescence technique were applied. Mouse anti-human keratin type 19 monoclonal antibody was used to detect regenerative epidermal stem cells in wound tissues. Results: Epidermal regenerative stem cells emerged at 24 hours post burn, and the number of epidermal regenerative stem cell increased on day 4 post burn. On days 7 and 14 post burn, the number of epidermal stem cells increased to the peak level. On days 21 and 28 post burn, it decreased and disappeared gradually as burn wound progressed to healing. Conclusion: MEBT/MEBO has the effect of promoting the activation and proliferation of epidermal regenerative stem cells in ...