摘要：剖宫产是运用外科手术的方式剖开腹壁及子宫,取出胎儿,其较顺产产妇而言存在手术性创伤,也存在较多并发症,其中剖宫产手术部位感染(Surgical SiteInfection, SSI)是发生率较高的并发症.感染对于产妇的恢复及新生儿有着极为不利的影响,由于手术伤口感染的直观可见,常常导致产科医疗纠纷的发生,影响医院的声誉、品牌,严重者引起医院感染暴发,更给医院带来难以估量的损失.因此目前对于剖宫产手术切口感染的研究受到广泛关注.笔者查阅相关文献,对影响剖宫产 SSI 的高危因素、预防、治疗及研究进展进行综述,除了采用常规的外科治疗技术处理创面外,近些年来也有不少使用密闭负压引流(Vacuum S...

摘要：目的:探索利用干细胞培植技术体外再生复制组织器官,并在体内验证.方法:取孕17天胚胎小鼠肠组织块在体外培养,实验分对照组和实验组,实验组培养液中加适量的促使肠粘膜复制的组合物GIC.连续观察、记录各组组织细胞生长情况.另在小鼠胃溃疡模型、胃和十二指肠溃疡病人观察GIC的疗效.结果:胚胎鼠小肠组织块体外培养,对照组10天后逐渐死亡;而实验组则持续生长、增殖、不断复制形成新的粘膜组织.GIC对动物和人消化道溃疡也有明显疗效,可使粘膜组织再生修复,无瘢痕愈合.结论:体外复制肠粘膜组织器官是完全可以实现的,这不仅具有重要的组织修复医疗价值,而且为人体生命科学研究提供了...

摘要：Objective The present study aims to explore the individualized treatment options for multisite pressure ulcer (PU) at various stages in elderly patients with multiple medical conditions. Methods Stages 1 and 2 PU at 146 sites were treated with closed negative pressure suction combined with continuous micro-oxygen perfusion and the local application of foam dressings, silver ion dressings, and moist burn cream. Stages 3 and 4 PU in the sacrococcygeal region were treated with skin or myocutaneous flap transplantation. Results Stages 1 and 2 PU healed after treatment with closed negative pressure suction combined with continuous micro-oxygen perfusion and dressing changes. One case died during hospitalization due to an illness. Skin or myocutaneous flap repair was conducted in 34 cases of stage 3 or 4 PU in the sacrococcygeal area. Of these cases, 28 achieved primary healing, and 6 required two or three surgeries, 5 of which received micro-skin implantation. In addition, 10 small deep PU at other sites were repaired by direct excision and suturing or local flap repair. Seven cases were transferred to other departments or hospitals due to concomitant diseases or were discharged automatically without surgical treatment. Conclusion Home care for geriatric patients is difficult. PU often occur at multiple sites because of the duration of various pressures, and different sites may demonstrate different stages because of varying degrees of pressure. When actively treating stages 3 and 4 PU, the trauma management of stages 1 and 2 PU should not be neglected.

摘要：Background and Aim: Natural topical products have been used to enhance wound healing, especially in immunocompromised animals. The aims of this study were to evaluate and to compare the effects of moist exposed burn ointment (MEBO) and honey on the healing of full-thickness skin wounds in immunocompromised dogs. Materials and Methods: The study was conducted using 12 adults, apparently healthy mongrel dogs. Immunosuppression was induced in six dogs by oral administration of prednisone (2 mg/kg) and azathioprine (2 mg/kg), once a day for 21 days. On each dog, a total of 9, 1.5 cm in diameter full-thickness skin circular wounds were created aseptically in the thoracolumbar area under general anesthesia using customized skin punch biopsy kit. In a random fashion, three wounds in each dog were treatment using MEBO (contains b-sitosterol, baicalin, and berberine as active ingredients in a base of beeswax and sesame oil), honey or no treatment (control), once per day for 21 days. Wounds were grossly evaluated once a day for signs of inflammation or infection. In addition, biopsy specimens and digital imaging data of each wound were obtained on days 7, 14, and 21 for histopathological evaluation of the healing process. Results: Wounds in immunocompromised dogs appeared to heal significantly in a slower fashion than in non-immunocompromised counterparts. Digital analysis data showed that MEBO-treated wounds expressed better epithelialization area, faster contraction, and smaller wound area percentage when compared with honey-treated wounds. Histopathological analysis showed significantly higher angiogenesis scores in MEBO-treated wounds when compared with other treatments. Conclusion: Results of this study showed that MEBO resulted in significant enhancement of wound healing in both healthy and immunocompromised dogs. However, when compared to honey, the wound healing effect of MEBO was superior to that of honey.