摘要：Skin wounds represent an enormous clinical and financial problem in equine. The present study evaluated the effect of Panthenol gel and Mebo ointment on metacarpal wounds healing in donkeys. This experimental study was carried out on eighteen adult donkeys divided into three groups each of six donkeys. All animals were exposed to creation of 2?× 2 cm full-thickness skin wound on the dorsal aspect of the metacarpal regions of both forelimbs. All the wounds were cleaned daily with sterile gauze soaked with sterile distilled water. For the Panthenol gel group, 1 finger tip unit (0.5?g) of Panthenol gel was applied once daily over the wound surfaces. For the Mebo ointment group, 1 finger tip unit (0.5?g) of Mebo ointment was applied once daily over the wound surfaces. For control group, the wounds were cleaned with sterile gauze soaked with sterile distilled water without application of any treatment. The wound healing process was compared by gross observation, geometrical assessments of percentage wound contraction, percentage wound epithelialization, percentage wound healing, and histopathological examination. The wound contraction, wound epithelialization, and wound healing percentages in the Panthenol gel group were significantly higher than other groups and by the end of seventh week, all animals’ wounds in the Panthenol gel group had complete healing. Mebo ointment group had no a significant effect on wound epithelialization and wound healing percentages. In conclusion, the study recommended the use of Panthenol gel as an effective and low-cost wound healing promoting agent for full-thickness skin wounds in donkeys.

摘要：The time profile of total proteins and albumin in line with two amino acids, Phe and Glu, are of great importance due to their indicative value of the healing and/or deterioration of burn wounds. In this experiment, rats exposed to scalding that produced a second-degree burn were divided into four groups: control, placebo, MEBO ointment, and copper (I) nicotinate complex ointment (an antioxidant anti-inflammatory) for four weeks. The three treatments showed noticeable similarities in the Phe profiles, with a slight drop 24 hours post burn, a peak elevation by the second week, and a slight, insignificant decline by the third week, with the placebo group showing highest values over normal (P< 0.05). In the Glu profile, large differences were observed: two set profiles, one representing MEBO and copper (I) nicotinate showed one peak in the second week, and the other representing placebo showed two peaks in the first and third weeks. Albumin and total protein time profiles showed the same trend throughout the whole experiment, and are in line with a reformed metabolic state parallel to wound closure. These results reveal that MEBO and copper nicotinate have comparable effects on wound healing in scald burns, and that plasma Glu profile is a better systemic indicator reflecting the regularity and steadiness of the healing process in MEBO and copper complex treatment.

摘要：本文报道我院妇产科和烧伤科共同协作，在门诊于1992年2月初至1995年4月底，采用CO₂激光离断子宫颈息肉根蒂配伍MEBO纱条上药的方法，共治疗子宫颈息肉门倒，获得了一次性治愈的满意效果，治愈率为100％。笔者认为：本法水中病人不感任何痛苦，无出血。未毕配伍MEBO纱来贴敷根蒂残端之灼焦创面，可保障灼伤创面无感染，使创面下残存的有生机上皮组织按生理性地进行修复，愈合无废痕。临床效果可靠，无副作用，经随访半年，无复发，颇值妇科临床进步推广使用。

摘要：复发性阿弗它性溃疡是指口腔粘膜反复出现孤立的圆形或椭圆形小溃疡，且有剧烈疼痛的病灶。因其治疗较为困难，故治疗方法甚多，且疗效不一。自1991年1月至1995年7月，我们采用CO2激光烧灼后涂MEBO治疗50例，并同传统疗法进行了对比研究，认为效果满意。