摘要:Burns expose the deeper tissues of the skin or body to invasive microbes. Topical preparations for treating burn wounds, to be useful, should ideally have antibiotic power and promote healing. Silver compounds have been the mainstay of topical burn treatment for decades. However, most chemical substances retard wound healing. Several natural agents such as honey and moist exposed burn ointment (MEBO) are believed to protect wounds from infection and promote healing without causing any of the adverse effects of purified chemicals. In this study, we compared the wound healing properties of MEBO, a herbal preparation of Chinese origin, with silver sulphadiazine (SSD), a long-standing conventional burn dressing. Ten adult Sprague Dawley rats were divided into two groups. They were housed in separate cages and received partial-thickness burn wounds on their dorsal skin. They were then treated with MEBO and SSD. The wounds were inspected daily until day 8, when all the animals were sacrificed, perfused with normal saline, and had their wounds excised and prepared for histology. It was found that animals in both groups were well preserved. No clinical infections occurred. Wound healing was at an advanced stage by day 8 in all the animals. Clinical and histological examination showed that the two agents gave the animals comparable protection and healing possibilities. It is concluded that MEBO is a suitable and efficacious alternative to conventional silver-based topical therapies for treating partial-thickness burn wounds.
期刊论文
A Comparative Study of the Wound Healing Properties of Moist Exposed Burn Ointment (MEBO) and Silver Sulphadiazine
会议论文
5.12汶川地震期间在地震蓬使用MEBT/MEBO治疗烧伤创疡患者的体会
摘要:目的:观察地震期间在地震蓬使用湿润烧伤膏(MEBO)治疗烧伤、创疡创面的临床疗效。方法:对地震期间对40余例烧伤患者、20余例创疡患者全程采用皮肤再生医疗技术治疗,规范化应用。结果:60余例患者仅一例行微粒皮种植术后封闭创面,其余患者创面全部自行修复愈合,无一例发生感染,愈合后瘢痕治疗,关节处创面愈合后功能良好。结论:在自然灾害情况下,使用 MEBT/MEBO 可使创面引流通畅,对预防及控制感染,促进创面愈合,疗效可靠。
期刊论文
50例黄磷烧伤的早期削痂与涂布MEBO的治疗体会
摘要:作者自1991年1月至1992年6月共收治黄磷烧伤50例,其中最小面积1%,但为特殊部位(右眼周围)。最大面积为28%。25例深Ⅱ°烧伤,25例Ⅲ°烧伤。为了正确处理黄磷烧伤,提出四个不同时间处理办法:1,第一个24小时,用流动自来水冲洗,涂1%硝酸银,在暗室内去除余磷,检出磷颗粒,外敷5%碳酸氢钠溶液。2,第二个24小时,早期立即削痂,特殊部位削痂植皮。3,第三、四个24小时,采用削痂手术后,洗必汰敷料湿敷包扎,去除残余真皮内、脂肪内磷颗粒。4,第五个24,小时,涂布MEBO,采用湿润暴露疗法。通过时间步骤处理,早日削痂,赶在出现并发症之前。50例病人无一例出现并发症全部治愈,平均住院36天,治愈率为100%。
期刊论文
3?M antimicrobial incise drape combined with MEBO in wound recovery of postoperative hypospadias surgery
摘要:To evaluate the efficacy of different dressing methods in wound healing and the postoperative outcome in children who underwent hypospadias repair.