摘要：Secretome Dental Pulp Stem Cells have been proposed as a new alternative for wound burn. The aim of this study is to compare Secretome Dental Pulp Stem Cells and MEBO ointment against several fibroblasts and collagen in the healing process of superficial dermal burns. This study used a post-test only controlled group design by using 15 rats that were given superficial dermal burned wounds. Rats were divided into a negative control group of NaCl 0.9% (K1), a treatment group of MEBO (K2), and a treatment group of DPSCs-secretome (K3). Histopathology was done on the 5th, 14th, and 21st days post-induction wound burn. Network-prepared histopathology by colouring Messon Trichomes. Then, it was observed under a microscope with 200x magnification. Scoring in a way semi-qualitative for assessing fibroblasts and collagen. The total score of fibroblasts in the MEBO group was higher than the DPSCs-secretome group on day 5th. In comparison, the score for increasing the amount of collagen in the DPSCs-secretome group on days 5th and 14th was higher than the MEBO group. DPSCs-secretome has better effectiveness in increasing the amount of collagen but not better in increasing fibroblasts compared to MEBO.

摘要：Healing Second degree burns can be affected by the presence of bacteria. This research reveals the role of honey and MEBO in removing bacterial effects on healing. Pure experimental research method with a completely randomized design (CRD). There were 4 treatments, which were positive, negative, honey and MEBO treatment, each of which was given to rats with second degree burns. Wound healing and other parameters were observed on 7th, 14th and 21st days. The result was that the administration of honey as an antibacterial drug was very effective and gave healing on the 21st day to white rats. Giving MEBO as an antibacterial drug is very effective and provides healing on the 21st day to white rats. Giving honey is more effective than MEBO as an antibacterial drug and healing burns on 21st day against white rats.

摘要：The local treatment of burn wounds has long been a subject of debate. The objective of this study was to compare the cost and the effectiveness of Moist Exposed Burn Ointment -MEBO versus a combination of povidone iodine plus bepanthenol cream for partial thickness burns.

摘要：Skin wounds represent an enormous clinical and financial problem in equine. The present study evaluated the effect of Panthenol gel and Mebo ointment on metacarpal wounds healing in donkeys. This experimental study was carried out on eighteen adult donkeys divided into three groups each of six donkeys. All animals were exposed to creation of 2?× 2 cm full-thickness skin wound on the dorsal aspect of the metacarpal regions of both forelimbs. All the wounds were cleaned daily with sterile gauze soaked with sterile distilled water. For the Panthenol gel group, 1 finger tip unit (0.5?g) of Panthenol gel was applied once daily over the wound surfaces. For the Mebo ointment group, 1 finger tip unit (0.5?g) of Mebo ointment was applied once daily over the wound surfaces. For control group, the wounds were cleaned with sterile gauze soaked with sterile distilled water without application of any treatment. The wound healing process was compared by gross observation, geometrical assessments of percentage wound contraction, percentage wound epithelialization, percentage wound healing, and histopathological examination. The wound contraction, wound epithelialization, and wound healing percentages in the Panthenol gel group were significantly higher than other groups and by the end of seventh week, all animals’ wounds in the Panthenol gel group had complete healing. Mebo ointment group had no a significant effect on wound epithelialization and wound healing percentages. In conclusion, the study recommended the use of Panthenol gel as an effective and low-cost wound healing promoting agent for full-thickness skin wounds in donkeys.