摘要：目的:探讨三种治疗方法对大面积烧伤病人的治疗效果。方法:采用SD-Zn糊膏、0.5%碘伏、MEBO治疗大面积烧伤160例。结果:SD-Zn及碘伏组共80例创面全部愈合,其中23例遗留疤痕增生,MEBO组80例全部治愈,治疗时短,仅7例轻度疤痕增生。结论:三种疗法中,MEBO湿润烧伤膏治疗大面积烧伤,方法简单,疗效可靠,便于推广应用。

摘要：目的：为了揭示Ⅱ度烧伤创面早期应用正规MEBT的重要性及早期保留疱皮的临床意义。方法：选取Ⅱ度小烧伤创面，按就诊时创面情况分为正规MEBT与非正规MEBT两大组，非正规MEBT组中又分为疱皮完整与疱皮撕脱两小组，接诊后均用MEBO治疗创面，肉眼观察创面愈合情况。结果；Ⅱ度烧伤早期应用正规MEBT的临床疗效明显优于非正规MEBT的疗效，且有统计学的显著差异；Ⅱ度烧伤早期疤皮完整者比疱皮撕脱者创面感染率明显降，也有统计学的显著差异。结论：Ⅱ度烧伤早期应用正规MEBT治疗烧伤创面是取得最佳疗效的关键；烧伤早期完整疱皮是预防创面感染的有效屏障。

摘要：Moist exposed burn ointment (MEBO) is an oil-based herbal paste, purported to be efficacious in managing burn wounds and more commonly used in Asia and the Middle East. A PRISMA-compliant systematic review was performed to analyse the evidence for the use of MEBO on burn wounds. Wound healing rate was the primary outcome of interest. PubMed-listed randomised controlled trials (RCTs) comparing the efficacy of MEBO with placebo, standard care or other therapies in the treatment of partial thickness burns in adults and children were eligible for inclusion (November 2019). Six RCTs were eligible. The majority of trials comparing wound healing between MEBO and SSD favoured MEBO (two of three). There may be improved healing in MEBO-treated wounds vs. those treated with povidone-iodine + bepanthenol cream. There was no difference between MEBO and Acquacel Ag, but Helix Aspersa had faster healing rates than MEBO. However, all evidence was from moderately to poorly reported trials with a high risk of bias, thereby limiting the strength of this evidence. In conclusion, the evidence for MEBO in English-language literature was poor and inconsistent with respect to wound healing rate and analgesis compared to 1% SSD, Acquacel Ag, Helix aspersa cream and povidone-iodine + bepanthenol cream. Blinded RCTs comparing MEBO to both placebo and other common topical treatments may further improve the confidence in concluding their analysis. There is some evidence that MEBO is as safe as its comparators as shown by the low complication rate.

摘要：Objective: From molecular, cell and systemic clinical treatment three levels, this report revealed the mechanism of wound healing, the basic theory and the importance of clinical practice for the Burn Regenerative Therapy with MEBT/MEBO (BRT & MEBT/MEBO).Method: This report analyzed the importance and clinical curative effect for standardized appliance of BRT & MEBT/MEBO from two key points: 1) Liquefaction of necrotic tissue from burn wound; 2) Skin regenerationin situ. Result: There are three necessary conditions for skin physiologically repair and regeneration of burn wound: 1) The formation of moist physiological environment on burn wound; 2) The material foundation of life regenerative substances and histology for keratin-19 stem cells' regenerationin situ; 3) Standardized procedures and appliance of BRT & MEBT/MEBO, which is the guarantee of burn wound healing physiologically. Conclusion: The theory of “Potential Regenerative Cell" and the technique of “Stem cellin situregeneration" are ...