摘要：Method: Consecutive patients (n=105) with CPUs (n=218) treated at three different hospitals were randomized to receive Moist Exposed Burn Ointment (MEBO) dressings (Regenerative group, n=55 with 115 ulcers) or wet-to-moist saline dressings (Control group, n=50 with 103 ulcers). Data collected prospectively included demographics, clinical, biochemical and ulcer features. Ulcer surface area (SA) and healing index (HI) were calculated and compared at twoweek intervals for 12 weeks. Results: Sixty-one patients (58.1%) were male and 44 (41.9%) were female. Their mean age was 69.5 years. There was an increase in HI and reduction in SA starting at two and four weeks, respectively in the regenerative group. At 12 weeks, 61.7% (71/115) of ulcers treated with MEBO had complete healing (HI=1) versus 28.2% (29/103) of controls (p=0.000). None of the patients receiving MEBO had a HI of<0.5 at 12 weeks as compared to 25.2% of controls (p=0.000). Significantly (p<0.01) more grade 2-4 ulcers healed completely with MEBO by 12 weeks. No adverse effects or allergic reactions were noted by 12 weeks. Conclusion: In addition to its safety, MEBO significantly promotes the healing of CPUs with significant increase in HI of any given ulcer as early as two weeks of treatment, and significant reduction of ulcer SA starting at four weeks with complete healing of more than 60% of ulcers by 12 weeks.

摘要：Introduction and importance: Skin tuberculosis is a rare chronic skin disease caused by Mycobacterium tuberculosis. Due to variations in host immunity, as well as differences in the toxicity, quantity, and routes of invasion of Mycobacterium tuberculosis, different clinical manifestations can occur. Case presentation: A 60-year-old female with a history of SLE for 16 years presented with dark brown nodules and plaques on the left lower limb and dorsal hands for approximately 8 months, which worsened with erythema and ulceration over the last 3 months. Prior to this, she was diagnosed with Mycobacterium tuberculosis infection. Her ulcer progressively increased in size and number, accompanied by yellowish-white cheesy discharge. Diagnostic evaluations, including a biopsy, confirmed the diagnosis of NF. Subsequently, the patient underwent treatment with a combination of surgical intervention, pharmacotherapy, and other supportive measures, leading to improvement and eventual discharge. Clinical discussion: Unlike the classical presentations, this case report describes a rare manifestation of NF secondary to cutaneous tuberculosis complicated by SLE. This presentation poses challenges in diagnosis and treatment, emphasizing the significance of comprehensive debridement and combination therapy in such patients. Further research is necessary to validate its effectiveness across broader patient demographics, especially in pediatrics and pregnant women. Conclusion: This case highlights the rare association between NF and cutaneous tuberculosis. The report of this case, with its rare clinical manifestations, can serve as a good reference to reduce misdiagnosis of cutaneous tuberculosis and provide timely and effective treatment for patients.

摘要：Backgrounds: Burn, a damage and tissue loss caused by heat with a high morbidity and mortality, have a many variation and complex problem that require special management. After a period of shock, there were infections that threaten the burn patients. These hazards aggravate the wound to become wider, and it affects the mortality and the length of stay. That is why to reduce mortality rate and length of stay, we need a proper wound care.Methods:A retrospective descriptive studies was perform on 2b degree burn patients (20-25%) that treated with tangential excision and mebo or tangential excision and stsg. Data was taken from burns unit Cipto Mangunkusumo hospital in period of January to December 2011.Results: There were 30 patients (73.2%) that have been treat with tangential excision and mebo, and 11 patients (26.8%) that have been treat with tangential excision and stsg. The average length of stay for the tangential excision and mebo is 22.47 ? 23 days(SD 4.361), whereas patients with tangential excision and stsg is 15.82 ?16 days (SD 2.089). There were 8 patients (26.7%) with tangential excision and mebo that die, whereas patients with tangential excision and stsg were 2 patients (18.2%) that die. There were significant difference in the average length of stay (p = 0.018), but there was no difference in the proportion of patients dying status (P = 0.611).Conclusion:Wound care by tangential excision and stsg on 2b degree burn patient (20-25%), have a better outcome than patients treated by tangential excision and mebo.