摘要：干细胞是动物体内一种独特的基本细胞类型 ,当分化时 ,有些可发展成为特殊类型的细胞、组织和器官 ,另一些仍维持干细胞 ,准备替代机体损伤和衰老的细胞。它们本身能自我复制 ,以供机体终生组织更新的需要。干细胞的培育研究为人类治疗破坏性和消耗性疾病带来了新的希望。国外学者着重于干细胞的离体培育研究 ,而我国徐荣祥运用整体性原则构建了成年皮肤干细胞生长发育的微环境 ,已原位培植成功 ,使烧伤创面达到再生愈合。现就有关干细胞的研究进展作如下阐述

摘要：本实验采用测定家兔皮肤内琥珀酸脱氢酶(SDH)的方法,测定了不同大小皮块以及与湿润烧伤膏(MEBO)不同混合浓度时的皮肤SDH值,作为实验组;测定置于常规皮肤保存液中的小皮块SDH值,作为对照组。两组结果表明,不同大小皮块的对照组与实验组之间,其活性百分值曲线是相同变化趋势,而且活性百分值与混合浓度大体呈正相关。这表明湿润烧伤膏对皮肤SDH值无明显影响。

摘要：Objective The present study aims to explore the individualized treatment options for multisite pressure ulcer (PU) at various stages in elderly patients with multiple medical conditions. Methods Stages 1 and 2 PU at 146 sites were treated with closed negative pressure suction combined with continuous micro-oxygen perfusion and the local application of foam dressings, silver ion dressings, and moist burn cream. Stages 3 and 4 PU in the sacrococcygeal region were treated with skin or myocutaneous flap transplantation. Results Stages 1 and 2 PU healed after treatment with closed negative pressure suction combined with continuous micro-oxygen perfusion and dressing changes. One case died during hospitalization due to an illness. Skin or myocutaneous flap repair was conducted in 34 cases of stage 3 or 4 PU in the sacrococcygeal area. Of these cases, 28 achieved primary healing, and 6 required two or three surgeries, 5 of which received micro-skin implantation. In addition, 10 small deep PU at other sites were repaired by direct excision and suturing or local flap repair. Seven cases were transferred to other departments or hospitals due to concomitant diseases or were discharged automatically without surgical treatment. Conclusion Home care for geriatric patients is difficult. PU often occur at multiple sites because of the duration of various pressures, and different sites may demonstrate different stages because of varying degrees of pressure. When actively treating stages 3 and 4 PU, the trauma management of stages 1 and 2 PU should not be neglected.

摘要：Introduction The purpose of this manuscript is to investigate the treatment of skin soft tissue embolization or vascular occlusion after the injection of hyaluronic acid (HA) for Injection Rhinoplasty (IR) in Asians with a special interest in the time occurrence of the occlusion. Methods A total of 35 cases were evaluated after receiving HA injections for IR who presented with a vascular occlusive event. They were divided into three stages based on the time to embolization. Immediate, ≤5 hours; early, ≤3 days; and late, >3 days. There were two cases of immediate, 28 deemed early, and five late. Methods to prevent tissue necrosis are reviewed in the manuscript based on these stages. Results Skin color gradually recovered to normal after 11 treatments in 11 patients with mild embolization. No ischemic aggravation or skin necrosis was observed in 19 patients with moderate embolization; red scarring was seen in two and hypertrophic scar with uneven skin color in one patient. The five patients in the severe category had longer healing, more red scars, and more hypertrophic scarring. Conclusion The treatment of skin soft tissue embolization or vascular occlusion after HA IR in Asians can be effected by identifying the stage and degree of embolization and treating appropriately with the outlines presented in this manuscript.