摘要：目的探讨HCPT微创技术(高级电容场痔切除术)术后配合外换用药特点。方法回顾性分析735例混合痔治疗过程。结果全部病例顺利完成手术,住院4～5d,住院期间与回家调养都用湿润烧伤膏至创面愈合约22d。结论回诊随访显示,创痕平整无小颗粒状增生患者,痛苦小,恢复较快,疗效可靠。

摘要：目的:针对中药制剂湿润烧伤膏,建立其中罂粟壳所含罂粟碱、吗啡、那可丁、可待因、蒂巴因等5种化学成分的凝胶渗透色谱-超高效液相色谱-质谱/质谱联用的检测方法。方法:色谱柱为Phenomenex Kinetex HILIC 100A（100 mm×2.1 mm,1.7μm）;柱温为40℃;流动相为10 mmol/L甲酸铵（以甲酸调节p H值至3.0）及乙腈,梯度洗脱;流速为0.2 m L/min,以优化后的质谱参数采集信号。结果:各成分检出限浓度为0.1～0.5 ng/m L;定量限浓度为0.5～1.0 ng/m L;线性范围为各成分定量限¹00 ng/m L;在线性范围内相关系数均在0.99以上;平均加样回收率86.5%⁹9.6%。结论:本方法准确,灵敏度高,专属性好;能用于湿润烧伤膏中罂粟壳化学成分的检测。

摘要：Objective: Many topicals claim an efficacious role in skin scar management with limited evidence. Our aim is to present a clear format for functional testing of a skin scarring ointment, using noninvasive and invasive measurements, categorizing findings under the physiological, structural, and mechanical parameters of a scar., Approach: A double-blinded, randomized volunteer research study of 45 subjects receiving an ointment composing of natural ingredients against a widely used antiscarring topical used as a positive control with temporal sequential punch biopsies (up to 16 weeks) was evaluated using noninvasive quantitative devices and validated by gene and protein studies., Results: Outcome measures included physiological, mechanical, and structural features of scars. Significant non-invasive findings included an increase in skin hydration (p?<?0.05) at week (W) 4, 8, and 12, and elasticity (W16; p?=?0.009). These findings were validated by immunohistochemistry (IHC) and quantitative real-time PCR (qRT-PCR). Hyaluronic acid IHC (W4 p?=?0.014, W12 p?=?0.034, and W16 p?=?0.042), qRT-PCR (W16 p?=?0.049); Collagen I (W16 p?=?0.034, and 0.049) IHC and qRT-PCR, respectively. Collagen III qRT-PCR (W12 p?=?0.035, and W16 p?=?0.32); elastin IHC (W12 p?=?0.044); and fibronectin IHC (W4 p?=?0.009, W12 p?=?0.038, and W16 p = 0.026)., Innovation: Utilizing this model allows for quantitative, objective evaluation of any topical, where previously there has been a paucity of relevant methods to evaluate their effect., Conclusions: The positive effect of a topical formulation with an unknown mechanism of action on early cutaneous scar maturation over progressive sequential time points is now evidenced using noninvasive and invasive techniques with the findings categorized on the basis of scarring parameters.

摘要：To evaluate the therapeutic effects of moisture exposed burn ointment (MEBO) on phlebitis, seven electronic databases where checked until September, 2016 for randomized controlled trials (RCTs) of MEBO on phlebitis. Risk of bias was assessed using Cochrane handbook guidelines. Thirty eight randomized controlled trials met the inclusion criteria in which the aggregated results indicated that comparison revealed significant differences in total effectiveness rate of MEBO versus conventional therapy (RR=1.27, 95% confidence interval [CI]=1.06, 1.52, and P=0.009), and there were some beneficial evidence regarding the effects on reducing incidence of phlebitis MEBO versus conventional therapy in preventing phlebitis (RR=2.73, 95% confidence interval [CI]=1.94, 3.85, and P<0.00001). The evidence that MEBO is an effective treatment for phlebitis is encouraging, but not conclusive due to the low methodological quality of the RCTs. Therefore, more high-quality RCTs with larger sample sizes are required.   Key words: External application of moisture exposed burn ointment, prevention and (or) treatment, phlebitis.