摘要:Burn injuries are considered one of the major sources of trauma that might lead to substantial morbidity and mortality. Severe burns cause multiple organ dysfunction and even sometimes organ failure, leading to debility and subsequent scarring that affects the quality of life and mental health. Consequently, this study is designed to compare the outcomes of two burn treatment modalities in patients suffering from burn injuries who were admitted to the Burn Unit / AL-Hussein Teaching Hospital / Samawa / Al-Muthanna Governorate. A clinical study was established during the period from December 2018 to January 2022 60 patients of both sexes suffered from different burn injuries. All patients are treated with Moist Exposed Burn Ointment -MEBO- or with covered classic methods using silver sulphadiazine cream dressings. Follow-up of treated patients is done to evaluate the treatment outcome. Our study included 44 burned and 16 scalded cases of different age groups, with second and third burn degrees extending on different body surface areas ranging from 30-60% in males and 30-70% in females. Of 60 patients, 40 females (67%) were between 10 and 40 years old, and 20 males (33%) were between 3 and 36 years old. The mortality percentages were 7 (23.3%) and 2 (6.6 %) cases out of a total of 60 patients for the conventional method and MEBO-treated group, respectively. Sepsis was observed in most dead cases, manifested by foul-smelling wound discharge and necrotic non-viable wound tissues, in addition to pneumonia and bronchitis. Pseudomonas sp, Klebsiella sp, and Proteus sp were isolated from these cases by culture and sensitivity tests. In conclusion, this study showed that the MEBO cream application in treating burned injuries revealed dramatic curative hopeful results with less liability for infective and septic complications compared with the conventional method, represented by the Sulphadiazine cream application. The authors recommend using treatment in burn units instead of using the routine old conventional method to avoid the expected morbidity and mortality and gain acceptable cosmetic results.
摘要:Background: Burn healing is dependent on good wound care management. Infection is one of the cause of wound healing failure. Infectious wound should be treated immediately. Binahong’s leaves is trusted as traditional herbal medicine which is considered capable to help wound healing process. Patient and Method: A 35 years old women suffer from scald and got 3% surface partial thickness burn at her right hand. The patient was initialy treated by application of MEBO. After a week patient came and felt uncomforted with the gauze. So, binahong’s leaves was patched on her wound to help the wound healing process. Result: After a week with binahong’s leaves therapy, the epithelialization is good and there was no infection. The result is satisfactory. Conclusion: This study shows that binahong’s leaves can be used to help wound healing process.
摘要:This study investigated the types of phytosterols that exists in the aerial and root parts of Echinops heterophyllus and explored the antibacterial effect of these phytosterols against some pathogenic bacteria in comparison with Moist Exposed Wound Ointment (MEBO?) and gentamicin.Plant was extracted and phytosterols were isolated and purified from the crude extract of Echinops heterophyllus by using chemical method. Thin Layer Chromatography (TLC) detected the presence of steroids in the aerial and roots part and gas chromatographymass spectrophotometer GC/MS analysis was used to identify some of these compounds and among them were beta-sitosterol and stigmasterol. Standard dilutions of the phytosterols isolated from Echinops heterophyllus were made from 10-100%; its antibacterial effect had been examined by seeded agar method against Staphylococcus aureus and Pseudomonas aeruginosa.The effect of these phytosetrols against Staphylococcus aureus was more potent than against Pseudomonas aeruginosa.The minimum inhibitory concentration (MIC) was seventy mg/ml and the minimum bactericidal concentration (MBC) was eighty five mg/ml. This study illustrates that sitosterol isolated from Echinops heterophyllus has a greater inhibitory effect on the test bacteria than gentamicine and closer results to MEBO?. It can be concluded in this study is a good step to show the types of phytosterols isolated from Echinops heterophyllus and the antibacterial effectof these phytosterols in vitro against Staphylococcus aureus and Pseudomonas aeruginosa.
摘要:Extravasation injuries in the neonatal intensive care unit are not rare during parenteral hyperalimentation. There have been many different methods of management. We report five premature infants with wounds of hyperalimentation fluid extravasation managed by the antibacterial ointment (Terramycin ophthalmic ointment?) and sesame oil and a antiinflammatory herbal mixture (MEBO?). The mean gestational age of patients was 31+2 weeks (range, 28+4 to 35+6 weeks), and the mean weight at extravasation was 1,930 g (range, 1,140 to 2,680 g). Extravasation occurred within the mean of 32 days (range, 17 to 50 days). The method of dressing was application of a thick layer of this mixture covered by vaseline and wet gauze renewed at an interval of 8-12 hr after irrigating the wounds thoroughly with normal saline. The mean duration of dressing was 30 days (range, 20-50 days). The wounds had healed completely leaving a small size of contracture without functional abnormality. We conclude that this therapy may be considered for an alternative treatment and warrants clinical trials for the confirmation of the local management of extravasation injury.