摘要：目的:探讨湿润烧伤膏治疗糖尿病足溃疡及坏疽的临床疗效。方法:对77例(94条患肢)糖尿病足合并远端足趾溃疡及坏疽患者,在采用常规降糖、抗凝、溶栓、抗炎等基础治疗上,对其下肢闭塞动脉实施PTA术,对溃疡及坏疽肢体采用清创或/和局部截去坏疽肢体,术后分两组:对照组59条患肢给予常规换药;实验组35条患肢采用美宝油纱条给予覆盖创面换药,对比观察两者肉芽组织填充缺损封闭创面的时间,感染控制情况。结果:实验组的肉芽组织填充缺损封闭创面的时间(26.14天±4.01天)较对照组(30.31天±4.23天)明显缩短,实验组的局部感染控制显效率高于对照组。结论:美宝湿润烧伤膏结合PTA治疗糖尿病足溃疡及坏疽可使患肢肉芽组织填充缺损封闭创面的时间明显缩短,且皮缘长势好,基本不用植皮,而且能使患者的感染得到有效地控制,值得推广。

摘要：目的：探讨两种不同敷料联合自体微粒皮种植术对深Ⅱ度烧伤的疗效。方法：选取2018年9月-2020年10月在笔者医院就诊的90例深Ⅱ度烧伤患者，按随机数表法分为对照组和试验组，各45例。对照组给予湿润烧伤膏联合自体微粒皮种植术进行治疗；试验组给予水凝胶敷料联合自体微粒皮种植术进行治疗。比较两组患者疗效、创面愈合情况、温哥华瘢痕量表（Vancouverscarscale,VSS）评分、血清致痛因子水平及不良反应。结果：治疗3周后，两组患者总有效率比较差异无统计学意义（P>0.05）；试验组患者创面上皮形成时间、创面愈合时间及不良反应发生率数值均低于对照组（P<0.05）；治疗3周后，两组血清前列腺素E2（Prostaglandin,PGE2）、神经肽（NeuropetideY,NPY）、5-羟色胺（5-Hydroxytryptamine,5-HT）水平均降低，且试验组低于对照组（P<0.05）。治疗2个月后，试验组VSS评分低于对照组（P<0.05）。结论：与湿润烧伤膏联合自体微粒皮种植术治疗深Ⅱ度烧伤效果相比，水凝胶敷料联合自体微粒皮种植术治疗深Ⅱ度烧伤可提升创面愈合速度，降低血清致痛因子水平，减少瘢痕形成，且不良反应较少，值得临床应用。

摘要：Background: Scar formation is a natural part of the wound healing process. The aim of this study was to observe the therapeutic effect of MEBO Scar ointment in the prevention and treatment of incisional scars. Methods: MEBO Scar ointment was applied 3 times daily after surgical stitches were removed in the test group. Warm saline was used in the control group. Clinical efficacy was based on scar quality assessment measuring – itching relief, skin texture, dystrophy and color. The wound was assessed at pre-determined intervals over 120 days post-surgery for therapeutic effectiveness of the ointment. Results: A total of 90 patients, male and female, undergoing elective surgery between February and December, 2013, with mean age of 30 years were included in this study. At 120 days, MEBO Scar was found to be highly effective (scar disappearance, no itching with soft scar, skin colour close to normal tissue) in majority patients (75%); and the overall scar quality was found to be significantly better (p<0.001) for all parameters. Conclusion: When initiated early, standard use of MEBO Scar Ointment for adequate period of time sufficiently softens the scars to prevent proliferation and appearance disturbances, resulting in a cosmetically acceptable scar. Therefore, it may be recommended for the prevention and treatment of scars postsurgery.

摘要：Burn injuries are considered one of the major sources of trauma that might lead to substantial morbidity and mortality. Severe burns cause multiple organ dysfunction and even sometimes organ failure, leading to debility and subsequent scarring that affects the quality of life and mental health. Consequently, this study is designed to compare the outcomes of two burn treatment modalities in patients suffering from burn injuries who were admitted to the Burn Unit / AL-Hussein Teaching Hospital / Samawa / Al-Muthanna Governorate. A clinical study was established during the period from December 2018 to January 2022 60 patients of both sexes suffered from different burn injuries. All patients are treated with Moist Exposed Burn Ointment -MEBO- or with covered classic methods using silver sulphadiazine cream dressings. Follow-up of treated patients is done to evaluate the treatment outcome. Our study included 44 burned and 16 scalded cases of different age groups, with second and third burn degrees extending on different body surface areas ranging from 30-60% in males and 30-70% in females.  Of 60 patients, 40 females (67%) were between 10 and 40 years old, and 20 males (33%) were between 3 and 36 years old. The mortality percentages were 7 (23.3%) and 2 (6.6 %) cases out of a total of 60 patients for the conventional method and MEBO-treated group, respectively. Sepsis was observed in most dead cases, manifested by foul-smelling wound discharge and necrotic non-viable wound tissues, in addition to pneumonia and bronchitis. Pseudomonas sp, Klebsiella sp, and Proteus sp were isolated from these cases by culture and sensitivity tests.  In conclusion, this study showed that the MEBO cream application in treating burned injuries revealed dramatic curative hopeful results with less liability for infective and septic complications compared with the conventional method, represented by the Sulphadiazine cream application. The authors recommend using treatment in burn units instead of using the routine old conventional method to avoid the expected morbidity and mortality and gain acceptable cosmetic results.